Focusing on denizens of the fictional town of Mapleton, three years after the fateful day when 140 million people - 2% of the world's population - disappeared without a trace, the series reveals how the strain of an unprecedented calamity can turn people's faith.
A town searches for answers three years after hundreds of their own vanished in a global, rapture-like "Departure".
Mapleton, New York, small-town police chief Kevin Garvey juggles personal and professional challenges as the three-year anniversary of The Departure - when millions of people worldwide suddenly vanished - approaches.
In the wake of a series of disturbing encounters, Kevin visits a therapist. Tom finds himself in a precarious situation with Christine. Meg is asked to part with pieces of her past. Jill and Aimee tail Nora Durst, a local celebrity since her entire family disappeared.
In the face of dwindling church attendance and threats on his life, the Rev. Matt Jamison continues to preachhis gospel: that many who disappeared were sinners and not saints. Matt's campaign is detoured when he learns he may lose the church to foreclosure.
A nativity scene goes wanting sending Kevin scurrying to find the culprit. Tom and Christine run into trouble at a hospital and on the road. Kevin retrieves a surprise detainee from a neighbouring police station. The Guilty Remnant put their stamp on the holiday season.
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Laurie's resolve is put to the test in the wake of a brutal hate crime. After his latest initiatives to maintain the peace fall short, Kevin turns down an outside offer to rid the town of its problems. Matt brings his pulpit to the street, and Meg takes on a new role.
Nora Durst finds herself adrift during a Departure-related conference in New York. Agitated that her ID has been pinched, Nora scours the convention for her imposter, and ends up getting detoured by an amorous salesman, a best-selling author, and a rogue attendee.
After learning his father has escaped the psychiatric hospital, Kevin orders an APB to track him down. Jill attempts to break an endurance record. Holed up in Indiana, a disillusioned Tom makes an unsettling discovery.
Kevin fears he's losing touch with reality after finding himself in a difficult situation involving a leader of the Guilty Remnant. Meg loses control during another encounter with Matt. Jill confronts Aimee about her rapport with Kevin. Nora finds her privacy invaded.
Kevin tries to suppress his bad habits while tracking down a marauding deer. Laurie receives some not-unexpected news amidst a rising sense of foreboding. Tom connects with his past, against his better judgment. Nora has a job interview. Kevin Senior receives an honour.
An unexpected ally helps Kevin get out of a jam near the town of Cairo. Meanwhile, a Memorial Day initiative by the Guilty Remnant plunges the town of Mapleton into chaos. Holy grants a final wish. Tom copes with his new reality. Nora makes a life-changing decision.