With Leonard away, Sheldon and Penny spend quality time together sharing intimate secrets. Also, Wolowitz helps Raj get over his ex-girlfriend.
Leonard and Sheldon's friendship is tested; Wolowitz's relationship with his mom causes a threat to his masculinity.
When the entire gang competes in a scavenger hunt designed by Raj, it brings out the best - and worst - in everyone.
Beverly Hofstadter writes a psychology book about Leonard which Penny buys and reads. Sheldon wants to ruin something for Amy after she ruins an Indiana Jones movie for him and Raj and Stuart try online dating.
Amy starts working at Caltech which causes friction with Sheldon. Howard agrees with Sheldon who mentions this to Bernadette causing a big fight for the Wolowitzes.
Sheldon's latest scientific breakthrough leaves him feeling like a fraud and a romantic gesture between Howard and Bernadette causes Penny to up her game with Leonard.
When Professor Proton asks Leonard for help with an experiment, Sheldon retaliates by befriending Proton's rival, Bill Nye.
When a mistake comes to light, Sheldon makes Leonard walk a mile in his shoes; Penny decides to confront Raj's ex.
Sheldon protests when the gang drags him to Mrs. Wolowitz’s house for Thanksgiving. Meanwhile, Penny and Leonard must deal with a mistake from her past.
Leonard and Amy help Sheldon cope with the shame he’s feeling after his accidental contribution to science is disproved. Meanwhile, Raj must stay with Howard and Bernadette for a week.
While Sheldon is in Texas, the rest of the gang realizes how much he has changed their lives as they decorate the apartment Christmas tree.
When Penny’s big acting break on NCIS is a bust, Leonard struggles to help her, which results in Penny asking Leonard a bold relationship question. Meanwhile, Sheldon tries to learn how to be funny.
Sheldon tries to relax after he is forced to take a vacation. Meanwhile, Leonard struggles to be supportive of Penny after she quits her job, and Bernadette seeks Stuart’s help in replacing one of Howard’s comic books.
After the guys can’t get Comic-Con tickets, Sheldon tries to hold his own convention and winds up spending a wild night with James Earl Jones.
Sheldon and Amy go on a trip to wine country with Howard and Bernadette; Penny and Leonard rush Raj's dog to the vet.
Leonard buys a dining room table and it causes Sheldon to reevaluate the changes in his life. Meanwhile, Wolowitz is offered a chance to go back to space and Bernadette struggles with whether or not to encourage him.
Bernadette tries to negotiate peace between Sheldon and Wolowitz; Penny receives an embarrassing offer and Raj wants Amy to write to a woman on his behalf.
When Sheldon visits his Mom in Houston, he is forced to confront a new reality. Meanwhile, Raj’s ‘Murder Mystery’ party starts some fights within the gang.
While Raj is wracked with guilt when he tries to date two women at once, Penny wrestles with whether to take a role in a cheesy movie and Sheldon is torn trying to choose between two gaming systems.
Sheldon faces a personal crisis after deciding he’s wasting his time with string theory. Meanwhile, a double date between Raj, Emily and the Wolowitzes ends in embarrassment for Howard.
To prepare for a date with Emily, Howard acclimatizes Raj to horror movies. Penny and Sheldon are upset when they discover Amy and Bernadette lied to avoid hanging out with them.
As the gang celebrates Star Wars Day, Sheldon discovers he is having difficulty dealing with the death of Professor Proton.
A bad day causes Penny to reevaluate her life choices – including Leonard. Meanwhile, Howard and Bernadette struggle to care for Mrs. Wolowitz, and Raj gets relationship advice from Sheldon.
Sheldon get upset about his career, the destruction of the comic book store and Leonard and Penny's future living arrangements. Howard and Bernadette can't keep hold of a carer for his mother.