Section 20's Samuel Wyatt, Thomas "Mac" McAllister and Gracie Novin are reunited for a dangerous mission in Malaysia after a Russian plane with precious cargo crashes under suspicious circumstances.
Section 20 forges an uneasy alliance with Zarkova in hopes of tracking down a stolen nuclear warhead, but find their efforts undermined from within.
Section 20's search for the missing nuclear warhead leads them to India, where a powerful woman with a vendetta is linked to the weapon's heist.
Desperate to locate a pair of "nuclear suitcases", Section 20 leans on a corrupt lawyer - and on Zarkova - to crack an encryption code and lead them to a rendezvous with Vartak and Gopan.
After the suitcase nukes are stolen by a brutal drug lord in Myanmar, Section 20 rush to the Punchan Province in a desperate attempt to prevent him from selling them to a nefarious buyer.
After several close calls in a prison and at a local village, Section 20 finally closes in on the stolen nuclear weapons - but will they be able to wrest them from Zaza and his soldiers?
As Wyatt convalesces, Coltrane, Mac and Novin embark on a covert, 24-hour mission inside Russia to extract an FSB analyst with potentially vital information. Katrina questions Pavel's true identity, but chooses to stand by her commanding officer.
Coltrane defends his decision to go rogue with S20. After tailing Hassan and the nuclear suitcase to a deserted shopping mall in Jakarta, Wyatt and Novin face down threats from Komodo soldiers and, later, Colonel Aldo and his insurgents.
In pursuit of Pavel, Section 20 clashes with two other Russian renegades, Natasha Petrenko and Artem Orlov, as they attempt to purchase sophisticated software designed to short-circuit a ghost satellite containing precious cargo.
Section 20 faces an ultimate dilemma as it battles Pavel and his Russian turncoats for keys to Soviet-era missiles. The conflict takes S20 from a remote village in the Philippines to Saloglu, Azerbaijan, where long-range missiles are ready to be fired on the West.