The special Federal Bureau of Investigation Missing Persons Squad's sole responsibility is to find missing people by applying advanced psychological profiling to reveal the victims' lives.

Jack and his team search for an 11-year-old boy, Gabe, who disappears from a subway station en route to Yankee Stadium for what was to be his birthday celebration.

As a couple cross to their car after a day of shopping, Duncan realizes that he needs to go back into the store to retrieve his credit card. After Duncan walks away, his wife's car speeds off, leaving a bystander injured.

The agents' job is harder than usual because they must find a woman, who changes her appearance to suit whatever modeling or acting job she is seeking at the time.

Jack and his squad search for a young man, 17-year-old, who was last seen by the charismatic headmaster of Spalding Academy.

Jack and the team search for a New York businessman, who disappears after he checks in for a routine airline flight home.

Jack and his squad search for a toddler, Abby, who was snatched from a park playground while playing with another child.

Jack and the team search for a teenager, William Hope, who goes missing in a very bad neighborhood after a confrontation with a local bully.

The team investigates the disappearance of Anwar Samir, a Saudi Arabian medical intern who became upset when his boss refused to write a letter of recommendation for him, and his girlfriend declined his marriage proposal.

Jack and the team investigate a father and his daughter, who disappear during their regular morning routine.

The citizens of a small Long Island town are shocked when 13-year-old Annie Miller disappears on her way to school.

Jack and the team search for a pregnant woman, Kathy Dobson, who disappeared from a hospital before being told that she has serious complications.

Jack is distraught and defensive when Chet Collins, whose son has been missing for 6 years, decides to search for him on his own because he thinks Jack has given up hope of finding him.

Jack and the team search for an airline stewardess, Linda Schmidt, who disappeared on her way to the airport.

Jack and his squad investigate a bride, Audrey Rose, who disappears from her wedding celebration.

Jack and his squad search for a teenage girl, Clare Metcalf, who disappears from a mental hospital after she suffers an extreme psychotic episode

Jack and the team search for a recently retired U.S. Army officer who disappears following a dinner in his honor given by former members of his Vietnam platoon.

Jack and the team search for a tenacious television reporter after she disappears in the middle of a dangerous, high-profile investigation.

Jack's squad looks for a young, idealistic and dedicated schoolteacher, who disappeared after teaching a night class in the Bronx.

Jack and the team search for a boxer, Dante Jones, who vanishes before a much anticipated fight at New York's Madison Square Garden.

Jack finds himself at the center of an investigation into how missing persons cases have been handled, including such controversial cases as that of Graham Spaulding' the accused pedophile now on trial.

Jack and his team search for an office worker, Sydney Harrison, who disappeared from her building.

Jack's squad must determine the best course of action when Samantha is shot and possibly critically injured in a hostage situation.