Dr. Oliver Wolf reluctantly accepts a job at Bronx General Hospital where he's forced to work with a team of interns as they treat a mother who can no longer recognize her kids.

When a high school girls’ basketball coach is faced with a debilitating illness, Dr. Wolf must help his patient reconnect with her body before it’s too late.

A member of a biker gang seeks out Wolf's help as he grapples with life-threatening memory loss.

When a bloody bride stumbles into Bronx General, Wolf goes to extreme measures in a race against the clock to save her and her missing husband.

Wolf must help a Marine grapple with mysterious symptoms before the birth of his child.

Dr. Wolf and the interns go back to high school to treat a group of pregnant teenagers.

Dr. Wolf and the team perform their most experimental treatment yet: a brain computer interface implantation in their John Doe patient's brain.

When an elderly woman is brought in with signs of dementia, Dr. Wolf investigates whether she's suffering from a neurological disorder or having a late-in-life awakening.