Comedian Nikki Glaser has left Hollywood for her parents in St. Louis. While there, she rekindles a relationship with her ex-boyfriend, Chris.
While Nikki performs a sold-out show in St. Louis, a prank gone wrong has the police at her parent’s house looking for her.
While planning a baby shower for her pregnant sister, Nikki starts envisioning kids in her own future.
Nikki fears her act will embarrass Chris and her parents as she shares intimate details of her sex life on stage.
After finally consummating her relationship with Chris in Chicago, Nikki wants to have bigger conversations about their future.
Nikki feels her relationship with Chris isn’t progressing the way she wants it to, so she decides to explore other options.
Nikki's dislike of nature and "activities" is challenged by a visit to her parents' river cabin.
While in Los Angeles, Nikki quickly falls back into her old work routine and considers a permanent return to the big city.