New Amsterdam is still reeling from the pandemic as a plane crash lands in the East River. When investigators come to interrogate the flight crew, Iggy races to help the pilot uncover the truth. After one of his own contracts COVID, Max tracks down scarce medication.

Max is forced to face the heart-breaking consequences of one of his policies. Bloom comes to a startling realisation about Iggy.

Max resists an idea that could bring New Amsterdam more revenue. Iggy pushes back on the new telemedicine system. Sharpe uncovers a startling trend while treating a beloved former patient.

Max journeys to Connecticut to bring Luna back to New York but second-guesses his instincts when he sees her with her grandparents. Bloom takes action to ensure her staff feels safe at work while Reynolds takes a backseat in the cardiac unit.

When the hospital's blood supply is running dangerously low, Max concocts a plan to get New Amsterdam out of trouble. Reynolds realises he has a thing or two to learn from Bloom while making peace with his new position. Iggy helps a patient face their inner demons.

Max is on a mission to fix systemic racism at New Amsterdam. Bloom treats a patient who reminds her that things aren't as they seem. Sharpe is overwhelmed while tending to a family matter. Reynolds tries to keep his composure while treating a father and son.

It's National HIV Testing Day and Max has offered free care to all HIV+ patients. Bloom and Reynolds butt heads over their opposing bedside manners. Iggy eagerly awaits the return of a friend. Sharpe discovers that she may need more hands on with her niece.

Max is forced to examine the inequities in child labour for women of colour. Bloom must deal with an overcrowded ED. Sharpe helps Dr. Agnes Kao with a gut-wrenching diagnosis. Reynolds finds himself experiencing something new on the job.

Max is on a mission to deliver free broadband access. Reynolds treats a young girl with a gunshot wound. Sharpe gives difficult news to a long-time patient. Iggy is immensely proud of his patient's success but worries that he may be getting too close.

Max reckons with New Amsterdam's past. Bloom and Reynolds treat a patient in an unconventional relationship. Sharpe decides to take a stricter approach to parenting her frustrated niece. Iggy tries to connect with a patient desperate to have gastric bypass surgery.

Max implements sweeping changes to hospital sustainability practices. Bloom returns from vacation. Reynolds treats a young patient with deadly heat stroke. Iggy discovers a dangerous situation with a former patient.

A burst pipe plunges the ED into chaos. Iggy counsels two stressed out parents about their child. Gwen and Calvin have some devastating news for Max.

Sharpe offers help to a reluctant Mina. Max is faced with a tough decision about Luna. Bloom and Casey treat a patient who's been hiding a lifelong secret. Iggy finds himself in a dangerous quandary. Reynolds treats a heart transplant patient with astonishing symptoms.

Reynolds receives a dramatic offer. Max scours the hospital after he misplaces his wedding ring. Iggy contemplates a serious life change. Bloom learns some potentially life-changing news about Leyla.

Max works to find a new normal three months after the accident and the birth of his daughter. Kapoor grapples with the stigma of aging. Iggy has a successful day that inspires a life-changing idea. Reynolds deals with an unreliable new intern.

Max invokes a hospital-wide census in effort to get to know the staff of New Amsterdam on a deeper level. Reynolds takes a leap of faith that lands him in hot water, and Dr. Castro extends her treatment plan to more patients in the hospital.

Max takes a chance on a new assistant and goes toe-to-toe with the board on a new plan. Iggy struggles to figure out what is causing a unit-wide illness. Kapoor receives some shocking news.

When Iggy and Kapoor discover a patient might be suffering from lead poisoning, they are forced to take on the city. Max's unsolicited attempts to help a patient backfire.

When Sharpe has a case that hits close to home, she and Max team up to make things right for the patient. Meanwhile, Iggy and Bloom are forced to make a tough call on a unique situation.

When a group of women on a retreat end up in the ED, Max gets some troubling information that could put a patient in jeopardy. Meanwhile, Sharpe and Kapoor work together to mend fences between two feuding sisters.

When Kapoor introduces a patient to Iggy's PTSD group, a creative treatment plan causes turmoil. Sharpe discovers a long-kept secret regarding a patient that leads to trouble for Max and the board.

Sharpe lands in hot water when she goes out on a limb for a patient. Max's grief comes to a head, while Bloom takes a major step in her recovery.

When an inmate comes in with an entirely preventable illness, Max, Sharpe, and Iggy head directly to the source - Rikers Island. Meanwhile, Bloom struggles with her recovery, and Reynolds gets news that could change his life.

With the hospital on lockdown after the Rikers patients' escape, Sharpe and Max find themselves in a situation that could cost them their lives. Meanwhile, Bloom must put aside her pain to help a patient in need, while Iggy is forced to face the issues in his marriage.

Max and Luna make friends in an unexpected place as he struggles with the realities of being a single father. Meanwhile, Kapoor takes a big step in order to help his family.

Sharpe has an important realisation that will affect her career. Meanwhile, Max and Reynolds take on uncharted waters when a young patient comes to New Amsterdam with symptoms of a heart attack.

The doctors stop at nothing to help their patients following a shocking realisation that prompts a change in the hospital. Meanwhile, Reynolds must make an important decision in his career.

Max races against the clock to rearrange the budget when faced with employees going unpaid, while Kapoor is presented with a device that's the future of medicine. Meanwhile, Iggy goes against the norms to prove a diagnosis and Bloom gets an unexpected visitor.

When tasked with turning the opioid epidemic around, Max shuts down the ED and proposes a massive change. Meanwhile, Sharpe goes great lengths to prove a point.

Max, Bloom and Reynolds frantically recount a patient's past encounter that could throw them into a massive lawsuit. Meanwhile, Iggy confronts a local middle school about its teaching policies, and Kapoor lets his superstitions take over.

Max searches for a solution to crowdfunding after his eye-opening appearance in a viral "Go Fund Me" video. Reynolds takes his last laps at the hospital while Kapoor helps a former pilot deal with his life as a paraplegic.

When multiple patients begin to show similar, alarming symptoms, Sharpe and Bloom scramble to figure out the root of the issue. Meanwhile, Max meets a child with a rare muscular disease and desperately tries to get him into the only clinical trial in the country.

Bloom, Iggy and Reynolds rally around Max as he deals with the fallout from Helen's decision. Bloom gives extra space to Leyla but she's in for a surprise. Reynolds and Wilder help a terminal patient realise his dream. Iggy has a breakthrough with a challenging patient.

Max tests a new cost-saving programme that could help the hospital and its neediest patients. Wilder struggles with a patient's decision to refuse life-saving surgery. Reynolds comes to a realisation about his father's behaviours. Iggy takes the leap into online dating.

An explosion at a wedding ceremony sends a stream of partygoers into New Amsterdam. While Max and Dr. Wilder scramble to find a rare blood type to save the groom, Reynolds and Bloom treat a couple with bizarre injuries; Iggy helps a young girl out of a catatonic state.

Max mandates a personal health day for the staff and is met with surprising resistance. Reynolds is intrigued by a persuasive new member of the staff. Bloom struggles after being taken off an essential medication. Wilder is convinced by Max to get much needed surgery.

Max endeavours to save a nurse who has become the subject of a dangerous malpractice probe. Reynolds goes the extra mile to help a group of patients who are being poisoned in their own building. Bloom makes a startling admission to her sister.

Max goes on a mission to make New York safer. Iggy helps a family come to terms with their deaf child’s inability to communicate.

The New Amsterdam staff grapple with the aftermath of the recent Supreme Court decision on abortion rights. Wilder counsels a woman whose pregnancy puts her life in danger. Max endeavours to find a healthcare solution for out-of-state patients.

Max discovers a revenue-generating department at the hospital that has legal implications. Iggy discovers a janitor with otherworldly talents. Reynolds treats an inspirational patient and makes plans for his dad. Wilder's patient teaches her not to jump to conclusions.

Reynolds gets creative to help a prospective mother in need. Max takes a chance with Wilder and learns a hard truth. Bloom treats a young brother and sister in dire straits. Iggy reaches a decision about Martin.

Reynolds finds himself caught between a chance for love and an opportunity to spend precious time with his father. Bloom makes an unexpected move forward with her sister. Max helps a struggling ICU intern. Dr. Wilder is forced to make a choice.

When Helen Sharpe returns to New York, Max escapes to the wilderness on a corporate retreat with Bloom, Dr. Wilder and Iggy, but fun soon turns into catastrophe. Reynolds agrees to perform a risky surgery only to be faced with unexpected challenges outside his control.

Max and Wilder face a dilemma over approvals for a revolutionary cancer drug as Max learns a secret about his own bout with cancer. Reynolds goes the extra mile to correct a dire medical situation. Iggy tries desperately to help a woman in need.

Everyone's story reaches a surprising yet inevitable conclusion.

Inspired by the oldest public hospital in America, this unique medical drama follows the brilliant and charming Dr. Max Goodwin, the institution's newest medical director who sets out to tear up the bureaucracy and provide exceptional care.

Max navigates his diagnosis while Dr. Sharpe encourages him to make a plan. Meanwhile, Dr. Bloom encourages Reynolds to take a chance and Dr. Kapoor and Iggy work together to help a child.

Reynolds begins to build his department as Dr. Sharpe battles scepticism from a patient's parents. Meanwhile, Max helps Bloom find a solution for a pregnant patient in a tough spot, all the while continuing to avoid the reality of his diagnosis.

When Max volunteers New Amsterdam to take over for a short-staffed hospital nearby, things get chaotic quickly. Iggy has a crisis of conscience after receiving the news that funding for a garden has been granted and an eager resident learns a secret about Dr. Bloom.

A journalist visits New Amsterdam to shadow Max and learn about the hospital. Bloom and Reynolds have a major disagreement after she makes a call against protocol and Kapoor deals with issues from his past.

The pressure is on as Max takes on his first annual fundraising gala at the hospital and emotions are high as some of the doctor's families join them for the event. Meanwhile, Kapoor and Dr. Sharpe work together to find out what is making a father and son duo so sick.

With a big domino transplant procedure on the line, Max must decide if he can be present in the hospital while also dealing with his illness. Meanwhile, a bond with a patient makes Bloom consider her personal life and Iggy makes progress on a long-standing case.

A patient's treatment plan takes an unexpected turn when Max gets overly invested. Meanwhile, Reynolds celebrates his birthday with some help from the hospital and Kapoor grapples with a case that hits close to home.

Max convinces Dr. Sharpe to take a risk on his course of treatment and Bloom grapples with a difficult conversation. Meanwhile, Dr. Kapoor considers helping his son in a big way after some advice from a friend.

As Max fights for his life, New Amsterdam is in full swing with a pertinent heart surgery that is not covered by insurance and a potential nurses' walkout. As the team feels Max's absence, Sharpe must finally come clean about Max's condition.

Reynolds confronts a difficult episode from his past; Max distracts himself from chemotherapy by taking on the case of a frequent-flyer patient; Frome helps a young man suffering from severe delusions; Sharpe worries about Bloom's attempt to detox.

Tensions are high in the hospital as Bloom is overruled on a diagnosis. Meanwhile, Iggy notices that something may be amiss with one of the hospital's most respected surgeons.

Max continues to work to solve underlying problems within the hospital despite his continuing struggles with treatment. Meanwhile, Reynolds makes the choice to do a costly surgery to determine an elusive diagnosis and Bloom must face her personal demons head-on.

Sharpe struggles when a case hits too close to home and Iggy uncovers a patient's surprising past. Meanwhile, Floyd makes progress in his personal life after some difficult news.

Max bonds with the patients undergoing chemo with him, but a conversation leads him to struggle with his reality. Meanwhile, Reynolds has difficulty handling a personal matter regarding a patient's family and Iggy struggles with a realisation regarding his daughter.

When a history-making blizzard hits New York, Max and his staff must work together to keep their patients safe with little resources, even if it means taking to the streets of the city and braving the storm.

As the doctors continue to weather the storm without power, Max relies on an unlikely source to get the lights back on. Meanwhile, Reynolds must get creative as he continues to work to save Hugh with very few resources.

Reynolds struggles to help a young cystic fibrosis patient with curious symptoms while Kapoor finally comes face to face with Ella after their awkward encounter. Meanwhile, Sharpe takes a major step in her personal life.

When a NYPD officer is hit by a car in the line of duty, the hospital is turned upside down trying to save her. Meanwhile, Kapoor and Iggy work with a patient struggling with a previous surgery.

Max is forced to reckon with his diagnosis in a new way as things become more difficult for him. Meanwhile, Reynolds is forced to address what could have gone wrong in a recent surgery.

Max goes head-to-head with hospital administration when he comes up with a new plan for patients without insurance. Iggy struggles with an accusation brought against him. Sharpe navigates her role as deputy medical director.

Sharpe works on a creative way to help Max. Kapoor gets some surprising news. Reynolds takes a big step in his relationship with Evie. One of the doctors makes a life-altering decision.

Max and Sharpe wake up to a new, more personal dynamic. Iggy calls upon an old contact to help with an explosive situation. Bloom begins a tricky dynamic with her new ED residents and Reynolds finds himself in an awkward position with Dr. Baptiste and Dr. Lyn Malvo.

Max and Sharpe go public with their relationship at the hospital. The team struggles to keep a handle on an overcrowded and understaffed ICU and everyone must pitch in. Iggy's overly critical feedback alienates his residents.

Max advises a young student at a science fair but encounters legal complications with her brilliant invention. Bloom encourages Dr. Shinwari to be more aggressive in the ED. Iggy gets a lesson in humility. Brantley has a surprise for the staff.

Max struggles with a new fiscal reality at the hospital. Dr. Sharpe's on a mission to provide follow-up cancer screenings for patients before it's too late. Bloom grapples with Dr. Shinwari's new overnight schedule. Reynolds has an interesting discussion with Dr. Malvo.

Dr. Fuentes continues her quest to remake the hospital in her vision. Max goes the extra mile to help a patient in need. Dr. Sharpe and Iggy find themselves at odds over a very serious issue. Reynolds discovers the importance of personal obligations.

Dr. Reynolds and Dr. Malvo have a heart-to-heart with Dr. Baptiste. Max learns a little more about Sharpe when someone from her past resurfaces. Iggy plays referee between two young patients and their families. Dr. Wilder reconsiders Max's offer to join the staff.

Max and Bloom are shocked when a deadly ambulance crash reveals a dangerous plan. Dr. Fuentes pressures Iggy to take on patients. Sharpe realises her own cost-cutting has adversely affected her department. Reynolds, Baptiste and Malvo strive to reach an accord.

Max is faced with a wrenching decision when New Amsterdam falls prey to a massive ransomware attack.

Max takes drastic measures to help several undocumented immigrants after a fire destroys the church where they had sought refuge. Sharpe and Malvo assist a patient with a life-threatening condition. Dr. Reynolds is conflicted about his new position.

As Max and Dr. Sharpe prepare to depart for London, a deadly superbug hits the hospital and draws them back in. Leyla confronts Bloom about the secret she has been hiding. Iggy digs deep to help two grieving parents confront the reality that their son is gone.

Max and Helen settle happily into their new life in London. Dr. Fuentes takes over as medical director with disastrous effects. Bloom helps a patient who thinks he's cursed. Iggy develops a plan to get his psych patients gainfully employed.

Helen takes the reins at NHS Hampstead Hospital while Max gets creative to help a patient. Reynolds reaches a decision about Dr. Malvo. Iggy and Bloom help their patients understand the underlying cause of their stress. Dr. Wilder employs more unconventional techniques.

Max and Helen adjust to sharing their lives and their problems, including the challenge of Helen's mother. Bloom and Reynolds treat a family after their horrific car accident lands them in the ED. Iggy and Trevor reach a new understanding in their business relationship.

As the team gathers to mourn the loss of someone dear, Max and Helen realise the extent to which New Amsterdam has changed since they left. Bloom struggles with a big decision. Reynolds decides to take his concerns for his patients to a new level.

Max formulates a bold plan to help New Amsterdam before it's too late. Reynolds and Dr. Fuentes fight over how to handle a risky surgery. Dr. Wilder asks Dr. Castries for help with a patient with terminal cancer. Iggy helps a father and son deal with a shared trauma.

As the team gathers to mourn the loss of someone dear, Max and Helen realise the extent to which New Amsterdam has changed since they left. Bloom struggles with a big decision while Reynolds decides to take his concerns for his patients to a new level.

The New Amsterdam team continues to deal with the consequences of their big night out. Max and Helen discuss options for their future. Martin finally learns Iggy's secret. Bloom helps Leyla avoid a life-changing situation.

Max orchestrates a plan to get Dr. Fuentes terminated from New Amsterdam once and for all. Helen confronts her medical complication. Iggy helps two patients deal with a breakup, which forces him to consider his own marriage.

Max discovers a fatal flaw in Dr. Fuentes' scheme to purchase the UMI medical clinic, which could be her ultimate undoing. Bloom treats two students for life-threatening injuries and uncovers a dangerous situation. Reynolds helps two siblings confront a family crisis.

Max discovers the extent to which Dr. Fuentes' cuts are severely damaging New Amsterdam and decides it's now or never. Iggy takes an unconventional approach to reach a young patient in need. Reynolds and Wilder perform a risky, life-saving surgery on unborn twins.

When an elder care facility shuts down, New Amsterdam is forced to intake many new patients. Max struggles with his decision to head back to London. Reynolds takes his personal frustrations out on his department with near disastrous results.

As a monster hurricane approaches New York, Bloom and the team scramble to put measures in place. Max and Helen make plans for an intimate New York wedding as she returns from London. Iggy and Martin reach a crossroads. Reynolds finally makes contact with his father.